As the. Coronavirus Resource Center. Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy Continue. Twitter Facebook. This Issue. July 17,  First Page Preview View Large. Access through your institution. Add or change institution. The Lancet said it first published reports on January 24,  The first report described the first 41 patients from Wuhan, China, diagnosed with Covid The Lancet noted that the lead scientists and physicians on the study were from Chinese institutions and "worked with us to quickly make information about this new epidemic outbreak and the disease it caused fully and freely available to an international audience.
Read More. The second report , compiled by scientists and physicians from Hong Kong and mainland China, described findings that indicated person-to-person transmission of the novel coronavirus, according to The Lancet. Donald Trump has repeatedly promoted hydroxychloroquine's use, calling it a "game changer" in the fight against coronavirus.
He said he had taken the drug himself to try and prevent infection, despite the well-known side effects. The Lancet study was a "retrospective observational" study, using a data set from Surgisphere. Retrospective observational studies, which look backwards and examine exposures to suspected risks or protections, are more prone to error than prospective studies. Randomised studies, on the other hand, are seen as the gold standard in research.
These studies randomly assign a treatment to one group of people and a dummy to another group, so that the two can be compared. The Lancet study simply used a large amount of hospital data — now called into question — to see what effects hydroxychloroquine had on some patients that were administered the drug, compared to those who were not. The WHO's decision to halt its trials on hydroxychloroquine as a result of the study had knock-on effects across the medical profession.
French company Sanofi also temporarily stopped recruiting for its study into the drug. Both the UK and French studies have yet to resume.
However, the UK Recovery Trial only paused briefly before proceeding after making safety checks, and has signed up about 4, recruits. Swiss pharmaceutical company Novartis has also continued with its trial. The notoriety surrounding hydroxychloroquine may have contributed to the sheer volume of studies surrounding the anti-malarial drug. But that volume poses a problem of research balance in the race to find treatments for coronavirus, says Paul Glasziou, professor of Evidence Based Medicine at Bond University.
One example of that is the Oxford trial, randomised trials. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the lands where we live, learn, and work. What was the study published in The Lancet?
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