We, at Orthopedic Associates, pride ourselves in providing our patients the best possible care. As a component to this quality medical attention, we would like to provide you with the information that may assist you in managing your health. Glucosamine and chondroitin sulfate are nutritional supplements and are not subject to the same rigorous regulations required for prescription and non-prescription drugs.
Therefore, if you decide to take any supplements, you do so at your own risk. The information provided in this brochure does not replace the advice and guidance given by your doctor.
If you have any questions about this supplement, please ask your physician. Glucosamine sulfate and chondroitin sulfate are naturally occurring substances found in the connective tissues of the body, including the cartilage that covers the ends of bones in the joints. Glucosamine sulfate functions are the primary building block for proteoglycans, large molecules in cartilage that give it viscoelastic buffering properties.
When taken orally, glucosamine sulfate is absorbed readily into the system and can be traced to cartilage as soon as four hours after consumption.
Similar to non-steroidal anti-inflammatory drugs, glucosamine sulfate has been shown to have unique anti-inflammatory effects. Additionally, in some laboratory tests, the glucosamine supplement demonstrated a protective effect on the cartilage as well. These studies suggest that glucosamine sulfate may inhibit the breakdown of cartilage associated with osteoarthritis and may have the potential to help build-up cartilage.
Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information. Please try again. Something went wrong on our side, please try again.
Show references Glucosamine and chondroitin for osteoarthritis pain. Arthritis Foundation. Accessed Oct. N-acetyl glucosamine NAG. Natural Medicines. Glucosamine sulfate. Pizzorono JE, et al. In: Textbook of Natural Medicine.
Elsevier, Vasiliadis HS, et al. Glucosamine and chondroitin for the treatment of osteoarthritis. Supplements may help reduce the symptoms of arthritis in adults. Learn more here. Glucosamine: Should I try it?
Medically reviewed by Dena Westphalen, Pharm. What is glucosamine? Function Supplements Evidence Side effects Risks Takeaway Glucosamine plays a vital role in building and repairing cartilage. Share on Pinterest There is no conclusive evidence that glucosamine supplements can prevent or treat any conditions.
Other uses and evidence. Side effects. Exposure to air pollutants may amplify risk for depression in healthy individuals. Costs associated with obesity may account for 3.
Related Coverage. Is the placebo effect real? Medically reviewed by Timothy J. Legg, Ph. What are the health benefits of vitamin D? Medically reviewed by Debra Sullivan, Ph. What is the best diet for osteoarthritis? Medically reviewed by Natalie Butler, R.
The number of participants in the RCTs included in this article ranged from 30 to The trials lasted from three weeks to three years. The first trial involved people over two years. In this six-month trial, which included participants, glucosamine had a clear significant benefit over a placebo and an even stronger effect than paracetamol in improving both pain and function.
The 64 participants with osteoarthritis of the knee in this study received either mg glucosamine sulphate three times a day or mg vitamin E made from palm oil once a day for six months.
Both groups improved in pain and function, but there was no difference between them. After 12 weeks, there were no improvements in the placebo group but those who received glucosamine reported significant improvements in resting and moving pain, overall pain, stiffness and function.
The improvements in these final three measures lasted for 20 weeks. In the treatment group, reported side-effects were heartburn and an all-over itch. Results of this trial were given a lower weighting when we came to our conclusion about the compound. Two RCTs were conducted to evaluate the role of glucosamine hydrochloride in the treatment of knee osteoarthritis. A review article also looked at its effects for hip and knee osteoarthritis.
0コメント